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The Cancer Cell Therapy Showdown: CAR-Ts Versus CAR-NKs

 
• By Ayisha Sharma

Will CAR-NK cell therapies overshadow traditional CAR-T options for the treatment of some cancers? While preliminary data for CAR-NKs point to enhanced safety and solid tumor penetration, oncologists and executives discuss the pros and cons of these two approaches to cell therapy.    

NK Cells Attacking A Cancer Cell
• Source: Shutterstock

In 2017, the US Food and Drug Administration approved Novartis AG’s Kymriah for the treatment of patients with acute lymphocytic leukaemia (ALL). The decision marked a sea change – Kymriah became the first of several chimeric antigen receptor (CAR) T-cell therapies to enter the cancer market.

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