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Paradigm Plots Revival Of Butterfly Skin Drug After Amicus Deal

Regains Rights To Topical Whole-Body Treatment

 
• By Kevin Grogan

Chiesi-owned Amryt and Krystal Biotech have approved treatments for epidermolysis bullosa but Paradigm CEO Robert Ryan tells Scrip that SD-101, a topical cream he helped develop over 20 years ago, has the potential to be offer a far more extensive and efficacious solution for many more sufferers.   

butterfly
• Source: Shutterstock

The main focus for epidermolysis bullosa (EB) treatment may currently be on Krystal Biotech, Inc.'s gene therapy Vyjuvek, but newcomer Paradigm Therapeutics believes a wound-healing agent just acquired from Amicus Therapeutics, Inc. that previously failed late-studies has the potential to help far more patients who have the rare genetic condition where skin can tear at the slightest touch.

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