Odd Coupling: J&J, RallyBio Collaborate As Only Firms Focused On FNAIT

While not co-developing each other’s drugs, J&J and financially troubled RallyBio are working on complementary approaches to the rare disease fetal and neonatal alloimmune thrombocytopenia.

Fetal
RallyBio hopes its antibody can prevent the rare disease FNAIT • Source: Shutterstock

About two months after announcing that it was reducing its workforce by 45% and focusing on two core R&D programs, Rallybio Corp. has gotten support from pharma giant Johnson & Johnson for its efforts to develop a therapy to prevent a rare disease that can cause uncontrolled bleeding in fetuses and infants. J&J has nipocalimab in Phase III to treat the disorder – fetal and neonatal alloimmune thrombocytopenia (FNAIT) – so the companies decided to make their efforts complementary while stopping short of a co-development arrangement.

More from Rare Diseases

More from Scrip

Roche’s Brain Shuttle Delivers In Alzheimer’s, Moves Ahead To Phase III

 

By allowing it to enter the brain more easily, trontinemab’s brain shuttle brings more patients to ‘amyloid zero’ levels faster, and with fewer brain swelling side effects.

Compass’ Bispecific BTC Contender Meets Phase II/III Endpoint

 
• By 

Compass' bispecific antibody tovecimig hits primary efficacy endpoint in Phase II/III top-line data in advanced biliary tract cancer, and may have class side-effect advantages. But additional survival data may be needed to support US approval.

AZ’s Oncology R&D Head On China’s Scientific Promise And True Innovation

 

AstraZeneca remains committed to investing in R&D and alliances in China, where Susan Galbraith, the UK major’s head of oncology R&D, sees innovation eventually reaching parity with the US and Europe.