Zenas Raises $200m For Bifunctional Antibody In Autoimmune Diseases

Obexelimab Is In Phase III In IgG4-Related Disease

Zenas BioPharma plans to have data from four trials – two under way and two starting this summer – for obexelimab, which targets CD19 and FcγRIIb, within about a year and a half.

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Zenas will increase its headcount by 20% • Source: Shutterstock

Zenas BioPharma is ahead of the pack compared with most companies advancing CD19-targeting therapeutics for autoimmune diseases, with plans to report Phase III results in IgG4-related disease and Phase II results in three other indications within the next year and a half or so. The company announced on 7 May that it closed a $200m series C venture capital round to finance the ambitious development program for its bifunctional antibody obexelimab while keeping an eye out for other potential drug candidates.

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