Novartis will bolster its neurodegeneration pipeline and specifically its Huntington’s disease portfolio in a license-and-collaboration deal with PTC Therapeutics announced on 2 December that analysts called a great financial return for PTC. Novartis will pay $1bn up front for Phase II small molecule RNA-splicing candidate PTC518, with potential for significant earnouts and profit-sharing going to PTC as well.
PTC Gets $1bn From Novartis For Phase II Huntington’s Candidate
Novartis will also pay up to $1.9bn for milestones and share US profits on the Phase II RNA-splicing candidate. PTC is discussing potential accelerated approval with the US FDA.

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