PTC Gets $1bn From Novartis For Phase II Huntington’s Candidate

Novartis will also pay up to $1.9bn for milestones and share US profits on the Phase II RNA-splicing candidate. PTC is discussing potential accelerated approval with the US FDA.

Novartis NIBR Cambridge, MA
Novartis adds another Huntington's disease candidate

Novartis will bolster its neurodegeneration pipeline and specifically its Huntington’s disease portfolio in a license-and-collaboration deal with PTC Therapeutics announced on 2 December that analysts called a great financial return for PTC. Novartis will pay $1bn up front for Phase II small molecule RNA-splicing candidate PTC518, with potential for significant earnouts and profit-sharing going to PTC as well.

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