Scant Intersection Between Patient-Centered Outcomes Research And Personalized Medicine’s Needs

 
• By Mark Ratner

On its face, comparative effectiveness research and its new cousin, patient-centered outcomes research, would seem to support, if not enable, personalized medicine. But as currently established in the US, there is little conceptual overlap. That’s largely because much CER and patient-centered outcomes research steer clear of anything that smacks of the development of cost data, which personalized medicine may need to truly make its value proposition.

Ezekiel Emanuel, MD, PhD, chair of the Department of Medical Ethics and Health Policy at the University of Pennsylvania, created quite a stir at the 7th AnnualPersonalized Medicine Conference in Boston last November. Claiming to be new to the issues around personalized medicine, he nonetheless proceeded to criticize it during his keynote address: for its rhetoric (personalized medicine is just targeted medicine, and medicine has been targeting for more than 150 years) and for its failure thus far to make a case for system cost savings. As with much new medical technology, real personalized medicine, he said, is unlikely to shrink costs and much more likely to increase costs – substantially.

That first point is debatable, but does suggest the challenge of adoption. Physicians often balk at any suggestion of being...

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