How GSK Is Driving Early Stage Research In Its DPUs

Most of GlaxoSmithKline's early stage research organizations, discovery performance units, survive a three-year review cycle, with co-localization, monetary incentives and career support leading a change of culture.

Three years on from start-up, most of GlaxoSmithKline PLC's core R&D organizational entities, Discovery Performance Units, have survived their first review, conducted at the end of last year, and are headed, "in the right direction," according to GSK R&D Chairman Moncef Slaoui. But should all Big Pharma companies structure their research this way? And what exactly are the attributes, cultural or otherwise, that are considered central to the success of DPUs? (See Also see "GSK Says R&D Productivity Up, But Story Is About Culture, Not Numbers" - Pink Sheet, 20 February, 2012.).

GSK's DPUs, or "biotechs on steroids" as one company researcher puts it, fed 27 drug programs into GSK's late stage pipeline between 2008 and 2011, a figure spotlighted by Slaoui...

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