Profitability: A Mixed Blessing for Celltech

Celltech's early profits have come from unexciting, low growth specialty pharma products rather than from a breakthrough in its innovative biotechnology pipeline. Now, the challenge for new CEO Göran Ando is to prove that Celltech's focus remains R&D, not specialty pharmaceuticals. With few promising late-stage in-house projects other than CDP 870, generic threats to the revenue source, and the straitjacket that comes with profitability, Ando has plenty on his plate. But his experience, both broadly within the industry and with CDP 870 in particular, suggest he's well placed to take Celltech to a new level of profitability.

Profitability was a long time coming for UCB Celltech . The company—the UK's oldest biotech—had been in business for over 20 years before announcing maiden profits in 2000. Yet when these profits came, investors weren't impressed. They'd bought into a classic biotech play—a company with a strong antibody technology base generating innovative new drugs for its pipeline—expecting that in the not-too-distant future one or more of those biotech products might succeed, delivering dramatic, breakout profits and sustaining exceptional future earnings growth. Indeed, they'd pushed up the company share price by over 110% in the six years since IPO on the back of these expectations (See Exhibit 1).

The size and source of Celltech's earnings were a disappointment. The £25 million ($37 million) pre-tax profit reported for 2000 and the £100 million reported since came almost entirely from...

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