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Strong PhII data in triglyceride reduction attracts partners to Essentialis

 
• By Mandy Jackson

Essentialis Inc. is in discussions with partners and potential acquirers as its moves into Phase III clinical trials for diazoxide choline controlled-release tablets, or DCCR, a drug that may cause dramatic reductions in triglyceride levels for high-risk patients who already are taking cholesterol-lowering medications.

Essentialis Inc. is in discussions with partners and potential acquirers as its moves into Phase III clinical trials for diazoxide choline controlled-release tablets, or DCCR, a drug that may cause dramatic reductions in triglyceride levels for high-risk patients who already are taking cholesterol-lowering medications.

DCCR is a potassium channel agonist is a proprietary crystalline salt of diazoxide, an old vasodilator that has been used for decades to treat hypertension. But in San Diego-based Essentialis’...

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