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Pfizer's Xalkori rides on in first-line NSCLC

 
• By Alexandra Shimmings

Pfizer is now poised to tout its anaplastic lymphoma kinase (ALK) inhibitor Xalkori (crizotinib) as a standard of care in both the first and second-line setting for patients with ALK-positive advanced non-small-cell lung cancer (NSCLC), following positive results in the Phase III PROFILE 1014 study.

Pfizer is now poised to tout its anaplastic lymphoma kinase (ALK) inhibitor Xalkori (crizotinib) as a standard of care in both the first and second-line setting for patients with ALK-positive advanced non-small-cell lung cancer (NSCLC), following positive results in the Phase III PROFILE 1014 study.

Top-line data from the study show that it met its primary endpoint of prolonging progression-free survival (PFS) in previously untreated...

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