Roche/Genentech's IL-13 inhibiting investigational severe asthma product lebrikizumab has failed in one of its two pivotal trials, adding to reservations about its future. Lebrikizumab is already trailing other biological competitors to the market and the lack of robust data at Phase III could well spell the end in this indication.
Top-line data from the two identical placebo-controlled LAVOLTA studies show that LAVOLTA II missed the primary endpoint of a significant...