In March, NICE, the HTA body for England and Wales, said it recognized the clinical benefits of Vertex Pharmaceuticals Inc.'sOrkambi (lumacaftor/ivacaftor) in the treatment of cystic fibrosis (CF) but treatment costs in relation to its health benefits were not sufficient to recommend its use (Also see "'No Surprise' Says Vertex As NICE Fails To Recommend Orkambi In CF" - Scrip, 23 March, 2016.). The SMC says it agrees with NICE's conclusion on Orkambi and will also not be recommending the use of Kalydeco (ivacaftor) in younger children.
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