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Entresto US Sales Barriers Set To Be Removed By Strong Guidance

 
• By Sten Stovall

Sales prospects for Novartis AG's struggling Entresto have been boosted – especially in the US – by new global cardiology guidelines issued by three organizations containing stronger than expected recommendations for its use in treating heart failure.

Pills and heart

Novartis' novel heart drug, formerly called LCZ696, was given a huge boost when experts from the American College of Cardiology, the American Heart Association and the European Society of Cardiology on May 21 announced that Entresto (valsartan/sacubitril) should replace old ACE inhibitors and ARBs in patients with adequate blood pressure and drug tolerance.

In the US, the twice-a-day medicine is now a standard therapy for heart failure with reduced ejection fraction (HFrEF) as...

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