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Phylogica Surges On Early CPP Cancer Results

 
• By James Dunn

Phylogica is continuing its strong financial year, with the company’s shares surging after it announced that a pilot study for its cell-penetrating peptides (CPPs) showed these were able to kill drug-resistant breast cancer cells in vivo, when linked with the cancer drug Omomyc.

The study also indicated that Phylogica Ltd.’s proprietary CPP fusion process significantly improved the efficacy of existing anticancer drugs including the EGFR inhibiting antibody cetuximab (Merck KGAA‘s Erbitux) and the chemotherapy agent docetaxel.

For example, a combination of cetuximab and a Phylomer CPP-Omomyc fusion was more than three times more effective at killing...

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Deal Build-Up Amid Early ‘Deep’ Response For IGI’s Trispecific In Myeloma

 
• By Anju Ghangurde

IGI CEO tells Scrip about the “very encouraging” feedback at ASCO to promising early data for the firm's first-in-class investigational trispecific antibody in multiple myeloma. Is a licensing deal in the offing?

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• By Dexter Jie Yan

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MetaVia Sees Obesity Opportunities Despite Challenging US Market

 
• By Jung Won Shin

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ASCO: Kite’s Dual-Targeting CAR-Ts Could Mitigate Toxicity, Resistance

 
• By Alaric DeArment

Gilead’s Kite division presented Phase I data for its next-generation CAR-T therapy KITE-363 in patients with B-cell lymphomas.

A MoonLake Buyout Would Boost Merck & Co’s Immunology Ambitions

 
• By Andrew McConaghie

As the patent protection clock ticks down on Merck’s flagship blockbuster Keytruda, the company is reported to be pursuing the inflammation and immunology biotech. Such a move would bulk up its sparse I&I pipeline.

Europe’s Drugmakers Lament EU Pharma Package

 
• By Kevin Grogan

EFPIA says reforms make the continent less attractive for innovative firms.