Takeda/Mersana Deal Adds To ADC Pipeline

Mersana Therapeutics is getting a vote of confidence from long-time partner Takeda as the two companies expand their collaboration in antibody-drug conjugates and plan to move a molecule into the clinic.

Mersana Therapeutics Inc. announced Feb. 3 that Takeda Pharmaceutical Co. Ltd. will pay $40m upfront for rights to XMT-1522, an antibody-drug conjugate (ADC) that targets HER2. Mersana will receive another $20m once an IND is accepted by the US FDA, which is expected in mid-2016.

Mersana will be responsible for preclinical and Phase I work, while the pair intend to work together on development beyond that point. Mersana retains US and Canadian rights to the...

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