When Novartis made clear its intention to acquire Chiron in 2005, a potentially important therapy for lung transplant patients was squeezed out by a numbers game. The drug candidate was an inhaled version of the immunosuppressant cyclosporine, and in a trial it had dramatically improved survival in lung transplant patients. Now, APT Pharmaceuticals takes over where Novartis left off, and it's preparing for a Phase III trial of the lung transplant drug.
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A GSK-Bharat Biotech deal on a shigella vaccine candidate has cast a spotlight on the disease, which is the second leading cause of diarrheal deaths in children below five. Scrip looks at data from Pharmaprojects, WHO and other sources to highlight why a vaccine matters and what pharma is doing.
In this week's episode: US policies in spotlight at BIO; Lilly’s Verve acquisition; UroGen’s bladder cancer approval; Ireland’s biopharma talent; and Korea proposes new AI R&D project.
Axcelead/Lotte Biologics/Kanaph and NextCure/Simcere also unveil ADC-focused pacts, plus deals involving Avata/Oceanus, GSK/Bharat Biotech, Cullinan/Genrix and more.
