It's very much early days for researchers and drug developers trying to tap the potential of microRNAs, the small snippets of nucleotides once considered genomic junk. But miRNAs may have a direct use as cancer biomarkers--a diagnostic application where the complex issue of correlating expression and protein function is less daunting. In a paper in PNAS this summer, researchers provide proof of concept for the use of miRNAs as blood-based markers for cancer detection.
Mark L. Ratner
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