“In the past there was a simpleminded notion that pain is pain is pain,” says Clifford Woolf, MD, PhD, director of the F.M. Kirby Neurobiology Center at Children’s Hospital Boston and a professor of neurobiology at Harvard Medical School. “Now we know there’s a whole series of different types of pain.” And that means pain, like other diseases where science is fast mapping previously hidden mechanistic pathways, will require drugs as differentiated as the disease.
Woolf is the neurobiologist credited as the first to show that abnormal central nervous system sensitization can provoke the pain hypersensitivity seen in chronic syndromes such as neuropathic pain. His...
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