Avalanche Biotechnologies Inc.
665 Third Street
Avalanche Biotechnologies Inc.
Ocular protein factories for eye diseases
Anti-angiogenesis drugs Lucentis and Eylea have proved game changers in the treatment of wet age-related macular degeneration, but to stave off AMD blindness, patients must submit every four to eight weeks for the rest of their lives to costly, painful, and potentially dangerous injections in the eyeball. Avalanche Biotechnologies Inc. hopes to replace that chronic regimen with just a single therapeutic gene injection that will set what it describes as an ocular protein factory into production that will stave off AMD pathology long term.
More from Archive
• By
Editor’s note: This is your final call to participate in the survey to better understand our subscribers’ content and delivery needs. The deadline is 20 September.
• By
Editor’s note: We are conducting a survey to better understand our subscribers’ content and delivery needs. If there are any changes you’d like to see in the coverage topics, content format or the method in which you receive and access Scrip, or if you love it how it is, now is the time to have your voice heard.
• By
CEO Paul Stoffels said gaining US clearance for an IND for its novel CAR-T product was demanding, but now opens up a pathway towards a pivotal study starting in 2025.
• By
A final rejection of Leqembi could also spell the same fate for Lilly’s rival drug but public outcry and demand for Alzheimer’s therapies might force the regulator’s hand
More from Scrip
Recent moves in the industry include changes at the top at Trogenix and Quetzal Therapeutics, plus Synendos Therapeutics gains a new CMO from Roche.
• By
Pointing to data that show a benefit in reducing viral load and the histological signs of the infection, Memo says its drug, potravitug, could become the first therapy to treat BK polyomavirus in kidney transplant recipients.
• By
In its Q2 update, Viking reported that Phase III trials of subcutaneous VK2735 are under way, and that it expects Phase II data for an oral formulation before year’s end.