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Roche: OAK Data Differentiates Tecentriq In Second-Line Lung Cancer

 
• By Emily Hayes

ESMO data suggest that patients with no expression of PD-L1 who took Tecentriq were able to generate an immune response, a result Genentech believes reflects the particular mechanism of action compared to PD-1 inhibitors like Opdivo and Keytruda.

With additional data from the Phase III OAK trial in hand, Roche has high hopes that the evidence that its PD-L1 inhibitor Tecentriq appears to generate new immunity in patients with no PD-L1 expression will help differentiate the product in the competitive programmed death checkpoint inhibitor space.

The company presented OAK data for Tecentriq (atezolizumab) in second-line NSCLC at the European Society of Medical Oncology annual meeting in Copenhagen on Oct. 9, following an earlier top-line release

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