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Combination Strategies A Common Thread In NASH R&D

 
• By Joseph Haas

Intercept continues to lead the non-alcoholic steatohepatitis race, but some analysts think Gilead is making up ground; data presented at AASLD shows those two, along with Allergan/Tobira and Bristol, are jockeying to produce combination regimens for the unmet medical need.

BOSTON – With hepatitis C on the decline, non-alcoholic steatohepatitis is becoming the focus of liver disease R&D. While Intercept Pharmaceuticals Inc. and Genfit SA have the early lead in drug development, recent deal-making by Allergan PLC and Bristol-Myers Squibb Co., as well as a reshuffled strategy at Gilead Sciences Inc., appear to have the competition in flux.

Intercept continues to lead the race to get the first drug approved for non-alcoholic steatohepatitis (NASH) with Ocaliva – but,...

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