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Juno Stresses Differences Between Its CAR-Ts As JCAR015 Trial Put On Hold Again

 
• By Emily Hayes

Juno stressed structural differences, safety record and potential of its JCAR017 CAR-T therapy during a Nov. 23 call about the disappointing hold on its ROCKET ALL study for JCAR015 – the second clinical hold for the company’s most advanced development program.

Juno Therapeutics Inc. is stressing the structural differences between the chimeric antigen receptor T-cell therapies in its pipeline after two fatalities caused it to put the brakes on a study of JCAR015 in adult acute lymphoblastic leukemia.

Juno announced the voluntary hold on the Phase II ROCKET clinical trial in relapsed and refractory ALL on Nov. 23,...

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