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Novartis, Kite Neck-And-Neck In CAR-T Race; Deaths Keep Juno In Third Place

 
• By Mandy Jackson

Novartis and Kite both are set to submit their CD19-targeting CAR-T therapies for US FDA approval in early 2017, while neurotoxic deaths for two of Juno’s product candidates cast doubts on its programs.

Both Novartis AG and Kite Pharma Inc. are stepping on the gas in the race to bring the first chimeric antigen receptor T-cell (CAR-T) therapy to the market, while Juno Therapeutics Inc. continues to lag behind, plagued by deadly cerebral edemas and a clinical hold.

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