Seattle Genetics/BMS Blood Cancer Tie-Up May Expand After Good Combo Data

Combo of Seattle Genetics' antibody-drug conjugate Adcetris and BMS's PD-1 inhibitor Opdivo demonstrates 90% objective response rate and 62% complete response rate in relapsed Hodgkin lymphoma, and further investigation of the pairing seems on the cards.

Seattle Genetics Inc. CEO Clay Siegall envisions a broader collaboration with Bristol-Myers Squibb Co. on blood cancer combinations following the release of encouraging data for the anti-CD30 antibody-drug conjugate Adcetris and the PD-1 inhibitor Opdivo in relapsed Hodgkin lymphoma.

Adcetris (brentuximab vedotin), which is partnered with Takeda Pharmaceutical Co. Ltd., is approved for classical Hodgkin lymphoma after the...

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