Alzheimer’s Update: Amyloid Hypothesis Lives On At Biogen, Lilly, Merck, Pfizer, Roche

Biogen rose and fell based on the company’s latest aducanumab results, but the Clinical Trials on Alzheimer’s Disease meeting Dec. 8-10 showed that regardless of Lilly’s Phase III solanezumab failure, companies continue to invest in amyloid and other hypotheses, including BACE, gamma secretase and other programs.

SAN DIEGO – The Clinical Trials on Alzheimer’s Disease (CTAD) meeting was a rollercoaster ride for Biogen, whose stock surged on the first day based on long-term Phase Ib results showing a reduction in amyloid plaques as well as improved cognition for patients treated with aducanumab, but shares slumped on the second day as a new safety concern spooked investors.

Biogen’s updated results from the PRIME clinical trial and extension study dominated the CTAD news on Dec

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