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Promethera Bets Liver-Derived Stem Cells Will Offer Benefits In NASH

 
• By Joseph Haas

Emerging Company Profile: Belgium’s Promethera presented preclinical data for HepaStem, its liver-derived stem cell candidate for NASH, fibrosis and acute-on-chronic liver disease, at the AASLD meeting. With what appears to be a solid safety profile, the company hopes to move into clinical studies in the near term.

As companies pursue many different targets and modalities in search of the first and best therapy to treat the broad unmet medical need in non-alcoholic steatohepatitis (NASH), Promethera Biosciences SA NV is nearing clinical development in NASH fibrosis for its liver-derived stem cell candidate HepaStem, which has shown promising efficacy in animal models and appeared to be safe for pediatric patients.

Promethera presented a late-breaking poster during the American Association for the Study of Liver Diseases (AASLD) meeting in November that...

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