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Incyte Further Enhances IO Pipeline With Calithera's Arginase Inhibitor

 
• By Joseph Haas

In its second cancer deal in two months, Incyte licenses a first-in-class asset expected to offer potential cancer immunotherapy synergy with IDO1 and checkpoint inhibition.

Incyte Corp. is gaining an asset from Calithera Biosciences Inc. that may offer an ideal therapeutic complement to the key asset in Incyte’s immuno-oncology pipeline, the Phase III IDO1 inhibitor epacadostat.

The collaboration and licensing agreement for the arginase inhibitor CB-1158, which has Incyte paying Calithera $53m up front, is the...

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