News that Lynparza (olaparib) works better than standard of care chemotherapy in treating a group of patients with HER2-negative metastatic breast cancer harboring germline BRCA1 or BRCA2 mutations has lifted hopes for the first-in-class drug – which is already been approved in the US for ovarian cancer – as well as for AstraZeneca PLC's overall DNA Damage Repair portfolio.
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