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AACR In Review: IDO Pushes Ahead, CTLA-4 Combo Lags Behind

 
• By Emily Hayes

Though momentum is building for IDO/PD-1 combos, it's still early days for new immunotherapy programs. Clinicians and investors weigh in on the latest data from the American Association for Cancer Research meeting and the state of the immuno-oncology field.

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Merck & Co. Inc. arguably got a leg up in its bid to lead immuno-oncology coming out of the American Association for Cancer Research meeting, between the rise of IDO as a target and new data showing disappointing efficacy for Bristol-Myers Squibb Co.'s CTLA-4/PD-1 combination in melanoma compared to PD-1 monotherapy. But development activity is intense and it's unclear where it will all end.

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