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Asthma Pipeline Pressure For AstraZeneca As STRATOS 1 Fails

 
• By Alexandra Shimmings

The failure of AstraZeneca's novel asthma therapy in its first pivotal trial is of little surprise but increases the pressure on its other late-stage asthma product in this key therapy area for the company.

Money down drain
Good money after bad? • Source: Shutterstock

The first Phase III trial of AstraZeneca PLC's investigational asthma therapy tralokinumab has failed to hit its primary endpoint, top-line data show, putting more pressure on its other asthma candidate benralizumab to counter the effects of generic erosion of its asthma franchise.

The study STRATOS 1 found no improvement in the annualized asthma exacerbation rate (AAER) over placebo in the overall population of severe asthma patients inadequately controlled despite receiving inhaled corticosteroids...

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