Janssen Pharmaceutical Cos. (a Johnson & Johnson company) reported positive Phase III data for Zytiga (abiraterone acetate) in hormone-naïve metastatic prostate cancer, providing a non-chemotherapy option for patients that is expected to change the standard of care. However, the market impact of Janssen's triple therapy could be limited due to a busy late-stage drug pipeline that includes novel mechanisms of action.
Data from the Phase III LATITUDE study, the subject of the June 4 plenary session at the American Society of Clinical Oncology's annual meeting in Chicago, showed that Zytiga plus prednisone in combination with androgen deprivation therapy (ADT) reduced the risk of death by 38%