The FDA has placed a clinical hold on three combination studies of Merck & Co. Inc.'s core immuno-oncology product Keytruda (pembrolizumab) in multiple myeloma, just weeks after enrolment in two of them was suspended on the back of reports of increased deaths in patients receiving the drug.
FDA Clinical Hold Hits Keytruda Multiple Myeloma Studies
Development of the leading immune-oncology agent has hit the buffers for multiple myeloma but failure in this relatively small market should not materially impact the product's prospects.
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A decision from the FDA is due by 28 September.