Shire May Spin Out Neuroscience Unit To Tighten Rare Disease Focus

The merger with Baxalta left Shire a portfolio consisting of 80% rare disease therapies, suggesting logically that the company might want to exit the primary care ADHD space.

Human brain illustrated with millions of small nerves - Conceptual 3d render

Shire PLC seems ready to make the move toward a pure focus on rare diseases. During its second quarter earnings call, the specialty pharma announced it had begun a strategic review of its neuroscience franchise – with all options on the table, including being spun out into a new publicly traded entity.

In an interview, CEO Flemming Ornskov said he would not speculate right now on what the outcome of the strategic review will be – the purpose is to determine if the neuroscience franchise and the remainder of Shire, mainly centered on rare disease therapeutics, can each stand on their own financially. During Shire's second quarter earnings call Aug

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