Roche's PD-L1 inhibitor Tecentriq (atezolizumab) was associated with a 38% reduction in the risk of disease worsening or death when used as part of a chemotherapy regimen for previously untreated advanced non-squamous non-small cell lung cancer in the IMpower150 study, the company announced on Dec. 7. This puts a concrete figure on last month's announcement that the Tecentriq combination had provided a statistically significant and clinically meaningful reduction in progression-free survival (PFS).
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