The data are from just four patients, but they were enough to send Adaptimmune Therapeutics PLC's share price up 19% on NASDAQ on March 15 as hopes were raised that its T-cell receptor (TCR) platform could be broadly effective across solid tumors. Shares closed at $10.94.
The company reported three partial responses (two confirmed and one to be confirmed), and one stable disease in the first four patients dosed in a Phase I/II study with its NY-ESO SPEAR T-cells in a second solid tumor: myxoid/round cell
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