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Will Pierre Fabre and Array Have Best-In-Class MEK/BRAF Inhibitor?

 
• By Kevin Grogan

Updated results from the COLUMBUS trial in BRAF-mutant advanced melanoma presented at ASCO revealed stellar overall survival data for the combination of encorafenib and binimetinib. Rivals Novartis and Roche will have noted that approval in the US is expected before the end of June.

Gears
Pierre Fabre and Array melanoma combo looks a good fit • Source: Shutterstock

Pierre Fabre Group and partner Array Biopharma Inc. are hoping for approvals on both sides of the Atlantic in the near future for their encorafenib and binimetinib combination treatment for melanoma, boosted by more positive data that have just been presented at the American Society of Clinical Oncology annual meeting in Chicago.

The companies announced updated results from the Phase III COLUMBUS trial in BRAF-mutant advanced melanoma which showed median overall survival (OS) of 33.6 months for patients treated with the combination...

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