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Celgene’s Positive Phase III Data For Otezla In Scalp Psoriasis Could Yield Broader Label

 
• By Joseph Haas

Celgene estimates 80% of moderate-to-severe plaque psoriasis patients experience the disease in their scalps, meaning positive data in this indication could broaden the market opportunity for Otezla substantially. Novartis’ Cosentyx got scalp psoriasis added to its US label in February.

Psoriatic Skin_1200x675

Celgene Corp. has for several years been talking up Otezla (apremilast) as a primary catalyst in its ambitions to build and maintain commercial heft outside the hematology and oncology arena. Positive Phase III data reported Oct. 8 in patients with scalp psoriasis could position Otezla for a broader label and a broader market opportunity in dermatology.

The small molecule phosphodiesterase 4 (PDE4) inhibitor was first approved for psoriatic arthritis by the US FDA in early 2014 and added moderate-to-severe plaque psoriasis to its label a few...

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