BridgeBio-Backed CoA Therapeutics Challenges Retrophin In Genetic Disorder PKAN

Emerging Company Profile: CoA Therapeutics plans to start a Phase I study of a CoA modulator in the rare, genetic disorder PKAN during the first quarter of 2020.

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Palo Alto, Calif., start-up CoA Therapeutics has set its sights on developing an oral drug to treat the debilitating and rare genetic disease pantothenate kinase-associated neurodegeneration (PKAN) as well as other genetic disorders involving the coenzyme A (CoA) pathway.

CoA Therapeutics was founded by BridgeBio Pharma in 2018 as a company developing therapeutics aimed at

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