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Another NASH Failure: Gilead’s Hits Keep Coming

 
• By Mary Jo Laffler

The failure of the STELLAR-3 trial of selonsertib had been widely anticipated following the failure in a sicker population in STELLAR-4.

Bright, blue green wave breaks on body boarder and sends red board flying at the Wedge, Newport Beach. - Image
Another wave of disappointment for Gilead

Gilead Sciences Inc.’s latest failure in non-alcoholic steatohepatitis (NASH) came as little surprise given the drug’s disappointing performance in its first Phase III trial, but it does raise the pressure on Gilead’s other NASH drugs and confuse the understanding about anti-fibrotics in NASH.

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