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Genfit Assesses Optimal Elafibranor NASH Combo Therapy Opportunity

 
• By Joseph Haas

As it nears the Phase III data readout for elafibranor in NASH, Genfit plans combo therapy studies to determine if a GLP-1 analog or SGLT2 inhibitor would offer the best therapeutic synergy, market potential and partnership opportunity.

Old buildings on the Grand Place square at the evening, Lille, France - Image
Based in Lille, France, Genfit is one of five companies to reach Phase III in NASH

Genfit SA is ready to begin combination therapy studies of its Phase III non-alcoholic steatohepatitis (NASH) candidate elafibranor with two classes of already marketed diabetes drugs, but that does not mean it has found a partner for a potential combo regimen. The Lille, France-based company wants to get proof-of-concept data first so that it then can choose the partner associated with the greatest opportunity.

Genfit research and development head Dean Hum explained that moving into combination trials is part of the launch strategy for...

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