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Vadadustat Emerges As Japan HIF-PHI Contender With First Filing Globally

 
• By Ian Haydock

Competition intensifies in novel anemia therapy space in Japan with first filing globally for Akebia/Mitsubishi Tanabe’s contender vadadustat, which could see its first launch worldwide in the country.

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First Filing For Novel Anemia Therapy Vadadustat • Source: Shutterstock

Mitsubishi Tanabe Pharma Corp. (MTP) has made the first approval filing globally, in Japan, for vadadustat (MT-6548), its oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) licensed from US venture Akebia Therapeutics Inc.

The pioneering regulatory submission, if approved, is expected to lead to the first launch of the molecule worldwide. It also...

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Citeline Japan Awards 2025 - Enter Now!

 
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The 14 July deadline for the Citeline Japan Awards 2025 in Tokyo is approaching fast, so here's a reminder to take a look at the categories and criteria and be sure to get those submissions in by this date. Sponsorship opportunities and tables for the event are also available.

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AstraZeneca Taps Into China’s R&D Engine With CSPC Alliance

 
• By Andrew McConaghie

After in-licensing a cardiovascular candidate last year, AstraZeneca has signed a strategic drug discovery alliance, which could generate billions of dollars in payments to the Chinese firm.

Is Zydus’s Agenus Deal Opportunistic Or Strategic?

 
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Will Zydus’s acquisition and licensing deal with Agenus turn out to be a strategic move towards building an oncology portfolio or an opportunistic one driven by a venture capital mindset?

Citeline Japan Awards 2025 - Enter Now!

 
• By Ian Haydock and Lisa Takagi

The 14 July deadline for the Citeline Japan Awards 2025 in Tokyo is approaching fast, so here's a reminder to take a look at the categories and criteria and be sure to get those submissions in by this date. Sponsorship opportunities and tables for the event are also available.