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Vadadustat Emerges As Japan HIF-PHI Contender With First Filing Globally

 
• By Ian Haydock

Competition intensifies in novel anemia therapy space in Japan with first filing globally for Akebia/Mitsubishi Tanabe’s contender vadadustat, which could see its first launch worldwide in the country.

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First Filing For Novel Anemia Therapy Vadadustat • Source: Shutterstock

Mitsubishi Tanabe Pharma Corp. (MTP) has made the first approval filing globally, in Japan, for vadadustat (MT-6548), its oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) licensed from US venture Akebia Therapeutics Inc.

The pioneering regulatory submission, if approved, is expected to lead to the first launch of the molecule worldwide

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