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Elevar Aims For Rivoceranib Turnaround After Positive Phase III Update

 
• By Jung Won Shin

Despite failing to meet the primary endpoint in recent top-line Phase III results, Elevar Therapeutics (formerly LSK BioPharma) is hopeful that rivoceranib still has potential in late-stage gastric cancer based on generally positive full efficacy data from the global Phase III study presented at ESMO.

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Rivoceranib To Become First Korea-Developed Cancer Drug Sold Globally? • Source: Shutterstock

US-based bioventure Elevar Therapeutics, formerly known as LSK BioPharma Inc., has unveiled new detailed data from the ANGEL Phase III study with rivoceranib (also known as apatinib), which together with best supportive care in patients with gastric or gastroesophageal junction cancer who had failed at least two prior lines of therapy showed generally positive efficacy.

The data, which followed disappointing top-line results in June (see side box), were presented at the European Society for Medical Oncology’s (ESMO) 2019 Congress in Barcelona, Spain, and marketed the first detailed

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Pipeline Watch: Thirteen Approvals And Ten Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.