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BMS’s Opdivo On Track For Esophageal Cancer Indication

 
• By Sten Stovall

Opdivo showed a 23% fall in the risk of death and 2.5-month improvement in median overall survival compared to chemotherapy in Phase III esophageal cancer trial.

Esophageal cancer
Opdivo Extended Overall Survival In ATTRACTION-3 Trial Versus Chemo • Source: Shutterstock

Results from Bristol-Myers Squibb Co.. and Ono Pharmaceutical Co. Ltd.’s Phase III ATTRACTION-3 trial showed Opdivo (nivolumab) ‘significantly’ extended overall survival (OS) compared with chemotherapy in patients with previously treated advanced esophageal squamous cell carcinoma, enhancing the PD-1 inhibitor’s likelihood of approval in that indication.

The trial data, presented at the European Society for Medical Oncology (ESMO) 2019 Annual Congress in Barcelona, Spain, showed Opdivo...

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