Intercept Says Data Indicate Pruritus Worries In NASH Could Be Overstated

11 Nov 2019

Patient-reported outcomes indicate patients don’t see itch as a major quality-of-life factor. Intercept also reports that adding earlier-stage patients to review of OCA shows better data on resolving NASH.

Young Doctor With Digital Tablet — Patient-reported outcome surveys indicate pruritus may not be a significant issue for OCA patients

A common take on Intercept Pharmaceuticals Inc.’s obeticholic acid (OCA) status as the likely first-to-market drug for non-alcoholic steatohepatitis (NASH) is that the drug will have a safety and tolerability profile that may cause clinicians and patients to not want to use it or to abandon it at the first sign of a better treatment option. Intercept presented data at the 2019 American Association for the Study of Liver Diseases meeting in Boston that it thinks shows that to be a lesser concern.

The New York-based firm presented data on 10 November indicating that patient-reported outcomes show pruritus may not be as critical...

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• By Mary Jo Laffler

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