Iterum Anxiously Awaiting Other Results After SURE 3 Failure

12 Dec 2019

• By Leah Samuel

Iterum’s antibiotic sulopenem missed its endpoint by the equivalent of one patient. The company believes the Phase III data could still support its NDA for urinary tract infections.

Illustration of bacteria on colorful background, model of bacteria, microbes, microorganisms, — Sulopenem has shown broad-spectrum activity against most Gram-positive and Gram-negative bacteria

Although Iterum Therapeutics PLC’s sulopenem missed the primary endpoint in the SURE 3 trial in complicated intra-abdominal infections, the four-year-old company believes the Phase III data could still be supportive of a new drug application if the firm’s other Phase III trials are positive.

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