Bispecifics Could Be A Threat To CAR-Ts, But Efficacy May Trump Convenience

T-cell-engaging bispecific antibodies emerged at ASH as viable competitors for autologous T-cell therapies, but while their off-the-shelf availability is intriguing, it may be too early to say if their safety and efficacy beats CAR-Ts.

3d illustration of T cells or cancer cells,3d rendering.
CAR-T competition? It may come from bispecifics that engage T-cells. • Source: Shutterstock

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