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FDA Approval Makes Deciphera’s Qinlock First Fourth-Line GIST Drug

 
• By Mandy Jackson

Qinlock (ripretinib), approved as the US FDA rejected Blueprint Medicines’ Ayvakit (avapritinib) in the same indication, is priced on par with the rival drug cleared in January for a narrower GIST use.

3d render illustration of human digestive system - front view
Qinlock is the first fourth-line GIST drug approved in the US

Deciphera Pharmaceuticals Inc. is prepared to launch Qinlock (ripretinib) for adults with gastrointestinal stromal tumors (GIST) previously treated with three other kinase inhibitors, including Novartis AG’s Gleevec (imatinib), via virtual meetings with cancer doctors after the US Food and Drug Administration approved the drug while simultaneously rejecting a rival product from Blueprint Medicines Corp. in the same fourth-line GIST indication.

Like all companies with new drug launches in 2020, Deciphera must deal with the challenges of COVID-19. However, the company has been preparing for a potential early approval of Qinlock...

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