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Pfizer’s Hopes For Ibrance In Adjuvant Breast Cancer Fall With PALLAS

 
• By Mary Jo Laffler

Ibrance (palbociclib) is unlikely to succeed in the adjuvant trial, the data safety monitoring board concluded. Pfizer has another adjuvant trial due later this year. 

Dividing breast cancer cell

Pfizer Inc.’s CDK4/6 inhibitor Ibrance (palbociclib) is now likely to miss out on the major chance for growth for the breast cancer drug, following the company’s announcement after the markets closed 29 May that the PALLAS study in adjuvant breast cancer was unlikely to meet the primary endpoint.

Pfizer had a two-year head start to establish Ibrance as the top drug in the CDK4/6 class, but it has...

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Boehringer Ingelheim Expects Two Key Approvals In Second Half Of 2025

 
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The Danish medical dermatology specialist doubles boosts its sales force ahead of the launch of Anzupgo.

Obesity Beyond GLP-1s: Amylins – The Next Frontier

 
• By Aakash Babu

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Where Next For Biologics In COPD After Roche’s Astegolimab Phase III Missfire?

 
• By Sushmita Panda

The Phase III failure could dent Roche’s hopes of entering the COPD market with its novel therapy, despite its success in a large Phase IIb trial. It also marks another disappointment for the anti-IL33/ST2 approach.