Pfizer Oncology Pipeline Shows Pivot To Targeted Therapies

Pfizer was heavily invested in immuno-oncology combinations five years ago, but following setbacks, the pipeline has shifted considerably, shaped partly by the acquisition of Array.

U turn
Pfizer has made big changes to its oncology pipeline • Source: Shutterstock

Pfizer Inc.'s oncology pipeline has undergone a significant transition in the last five years, moving away from what were at one time high-profile immuno-oncology assets toward new targeted therapies. The failure of immuno-oncology combinations to deliver paradigm-changing successes has led many cancer drug developers to reprioritize next-generation targeted therapies.

Pfizer showcased its oncology pipeline during an R&D overview on 15 September, highlighting a late-stage portfolio that includes only two...

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