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Vertex Suffers Setback In Its Search For Post-CF Blockbusters

Analysts Doubt Pipeline Potential

 
• By Andrew McConaghie

Vertex has become a biotech investor favorite amid the tumult of 2020, but the potential of its pipeline is now under question.

Vertex Corporate Headquarters
Vertex's shares were up 25% this year before the news of the pipeline setback. • Source: Vertex

Vertex has suffered a serious blow to its plans to build beyond its cystic fibrosis franchise, with the failure of pipeline drug VX-814.

The novel drug was in Phase II development for the rare condition alpha-1 antitrypsin deficiency (AATD), but will now be...

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